This new article in The Scientist discusses these 4 new CRISPR innovations, two of which I've also blogged about before (but check out the article for more comments from the authors…)
(1) using SCR7 to promote homology-directed repair (HDR) in mouse embryos;
(2) engineering cells to contain an inducible Cas9 gene;
(3) improved methods for directly delivering Cas9 protein into cells; and
(4) more thorough off-target identification using COSMID.
All interesting and worth reading about!