Tuesday, August 12, 2014

Seamless correction of beta-thalassemia mutations in iPSCs using #CRISPR and piggyBac transposon.

Efficient genome editing in human cells for therapeutic purposes will continue to be one of the most anticipated uses of CRISPR.  Here's a new, good example of this direction, from Genome Research.   

Seamless gene correction of ╬▓-thalassemia mutations inpatient-specific iPSCs using CRISPR/Cas9 and piggyBac.
Fei Xie, Lin Ye, Judy C. Chang, et al.
Genome Res. published online August 5, 2014 

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