Tuesday, June 10, 2014

Recent #CRISPR papers of note: Translocations and deletions in cells, and a review with nice figures from Zhang.

1.  Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system. R. Torres1, M.C. Martin2, A. Garcia1, Juan C. Cigudosa2, J.C. Ramirez1 & S. Rodriguez-Perales2.  Nat Commun. 2014 Jun 3;5:3964. doi: 10.1038/ncomms4964.
2. Characterization of Genomic Deletion Efficiency Mediated by CRISPR/Cas9 in Mammalian Cells.  
Canver MC1, Bauer DE2, Dass A2, Yien YY3, Chung J3, Masuda T3, Maeda T3, Paw BH3, Orkin SH4.  J Biol Chem. 2014 Jun 6. pii: jbc.M114.564625. [Epub ahead of print]

3. Development and Applications of CRISPR-Cas9 for Genome Engineering.  (Review). 
Patrick D. Hsu, Eric S. LanderFeng Zhang.  Cell, Volume 157, Issue 6, p1262–1278, 5 June 2014

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