New developments in CRISPR technology, with a focus on mouse and human cell applications.
Sunday, March 23, 2014
Interesting example of CRISPR mouse knockout strategies
Many traditional mouse knockouts have generated results that were not straightforward to interpret, or even controversial. CRISPR promises to allow more replication experiments, or varying targeted designs, to sort out some of these issues as discussed in the Prp/Prnp story: